General research into the effects of systemic low level laser

Low Level Laser Therapy is scientifically well documented for many indications; there are more than 100 double-blind positive studies confirming the clinical effect of LLLT. More than 2500 research reports are published. In 2005 the Postgraduate Medical Journal (81:436-441) published a scientific review of 100 scientific studies from Eastern Europe on the use of blood irradiation in the treatment of The study was conducted by T Moshkovska , J Mayberry from the Leicester General Hospital, Leicester, UK. The study was published under the name " It is time to test low level laser therapy in Great Britain" . The authors of the study have come to following conclusion: "The ability to non-thermally and non-destructively change cell function is known as laser bio-stimulation and is the basis for the current use of lasers in a number of medical fields. The worldwide interest in LLLT is illustrated by its use in more than 85 institutions in over 37 countries. Since the first study was reported in 1967, some 2500 papers have been published in a range of journals worldwide and the value of LLLT is much better reported than many believe. Its scientific background is sound enough to say that it is both safe and effective." T Moshkovska and J Mayberry, Postgraduate Medical Journal 2005; 81: 436-441 © 2005 Fellowship of Postgraduate Medicine.

For more information on the scientific research please refer to the book:

Michael Weber, Medical Low-Level-Therapy – Foundation and Clinical Applications, 2. Edition, 2015, ISLA Research Group Laser Therapy - Clinical Practice and Scientific Background by Jan Tuner and Lars Hode, or visit the research library on the website Tina Karu, The Science of Low-Power-Laser Therapy



Nicotinamide adenine dinucleotide (NAD) is a vitally important molecule found in all living cells. Its primary function was considered to be as a co-enzyme in the energy-harnessing processes within cells. Reduced levels of NAD+ will impact on cellular repair processes which could result in the development of disease and enhancement of the aging process. Every time we breathe, it burns the fuel in our cells and turns it into energy. In turn, the energy runs through our cells to create million of chemical reactions needed to be alive. This oxidative stress causes many diseases as well as the aging process.

Excessive oxidative stress is a feature of conditions ranging from neurodegenerative disorders (Parkinson's disease, Alzheimer's disease, Motor Neuron Disease), acute neurological conditions (trauma, hypoxia, epilepsy), drug and alcohol addiction, presumed auto-immune disorders (Chronic Fatigue Syndrome, Lupus, Fibromyalgia, Multiple Sclerosis, Rheumatoid Arthritis), genetic diseases (Muscular Dystrophies, Mitochondrial diseases, Huntington's Disease) and metabolic diseases (Diabetes type 2, respiratory and cardiovascular disease) as well as the aging process itself.

Picture of co-founder of NAD+ Arthur Harden



The NAD+ coenzyme was first discovered by British biochemists Arthur Harden and William John Young in 1906. They noticed adding boiled and filtered yeast extract accelerated alcoholic fermentation greatly in unboiled yeast extracts. They called the unidentified factor responsible for this effect a coferment.

Vitamin precursors of NAD+ were identified in 1938, when Conrad Elvehjem showed that live r has an "anti-black tongue" activity in the form of nicotinamide.

Then, in 1939, first strong evidence was found that niacin is used to synthesize NAD+. In the early 1940s, Arthur Kornberg made another important contribution towards understanding NAD+ metabolism, by being the first to detect an enzyme in the biosynthetic pathway.

The metabolism of NAD+ has remained an area of intense research into the 21st century, with interest being heightened after the discovery of the NAD+-dependent protein deacetylases called sirtuins in 2000, by Shin-ichiro Imai and coworkers at the Massachusetts Institute of Technology.


  • Chronic Fatigue Syndrome
  • Depression
  • Lyme's Disease
  • Alcohol Detox
  • Anxiety
  • Neuro-degeneration
  • Rheumatoid Arthritis
  • Anti-ageing

Fatigue and exhaustion

  • General fatigue and or exhaustion
  • Recovery after illness
  • Chronic fatigue/MS
  • Burnout syndrome
  • Cancer fatigue

Metabolic disorders:

  • Hypercholesterolemia
  • Diabetes

Cardio- vascular diseases:

  • Arteriosclerosis
  • Micro-Angiopathy
  • Coronary heart disease
  • Heart failure
  • Hypertension
  • Erectile dysfunction

Cardio- vascular diseases:

  • Arteriosclerosis
  • Micro-Angiopathy
  • Coronary heart disease
  • Heart failure
  • Hypertension
  • Erectile dysfunction

Immune system:

  • Allergies
  • Hay fever
  • Asthma
  • Autoimmune diseases
  • Rheumatoid arthritis
  • Multiple Sclerosis
  • Recurrent infections
  • Chronic infections (bacterial, viral and parasites)
  • Chronic and chronic recurrent chest infections
  • Influenza (recovery)
  • Lyme Disease
  • Chronic hepatitis
  • HIV
  • Low Immunity
  • Hashimoto disease
  • Multiple sclerosis
  • Psoriasis

Chronic pain

  • Fibromyalgia
  • Osteoarthritis
  • Migraines
  • Chronic head ache

Emotional health

  • Addiction
  • Autism
  • Depression
  • Anxiety disorder
  • Insomnia
  • Stress related conditions

Other conditions:

  • Irritable bladder syndrome
  • Chronic toxicity
  • Hearing loss
  • Tinnitus
  • Hormonal imbalances
  • Some forms of infertility
  • Macular degeneration
  • Osteoporosis
  • Performance improvement (sport)
  • Polyneuropathy
  • Chronic kidney disease, incl. renal failure
  • Chronic rhinitis and sinusitis

General effects:

  • Significant improvement of general fitness
  • Improved sleep and vigilance
  • Improved mood
  • Reduced drug consumption

Special effects:

  • Optimization of diabetic metabolism
  • Improved blood fat profile
  • Improved liver and kidney function
  • Reduction of relapse of chronic-inflammatory bowel disease
  • Improved general wellbeing and mobility in multiple sclerosis
  • Improved pain control in chronic pain
  • Improved tinnitus
  • Reduction of anti-hypertensive medication
  • It activates the parasympathetic activity of the autonomic nervous system counteracting the long term effect of stress on the organism.


For the full benefit of NAD+ therapy, it's very important that the highest grade of NAD+ and its sterility is used its advisable to check the cert of analysis.

What used to take up to 6 hours for a NAD+ infusion, can now be systematically delivered in 35 minutes as a result of many years experience with NAD+.